The Bills Mafia invades Arizona when Buffalo takes on Kyler Murray and the Cardinals.Week 10 of the NFL season has a couple of exciting games on the schedule including the Buffalo Bills (7-2) playing at the Arizona Cardinals (5-3). There’s also an NFC West showdown between the first-place Seattle Seahawks (6-2) and the LA Rams (5-3), who are fresh off a bye week.

Kyler Murray NFL Week 10 quickie preview Arizona Cardinals Buffalo Bills
Quarterback Kyler Murray of the Arizona Cardinals evades the Miami Dolphins defense. (Image: Chris Coduto/Getty)

The Pittsburgh Steelers also have a perfect season on the line with Big Ben sidelined with COVID. The 8-0 Steelers square off against the Cincinnati Bengals in a smashmouth divisional brawl.

The New Orleans Saints (6-2) have a five-game winning streak on the line when the San Francisco 49ers come to the Superdome. The Miami Dolphins (5-3) won four straight and have their eyes on a Wild Card berth after starting the season 1-3.

The Jacksonville Jaguars (1-7) lost seven games in a row. The Jags are on the cusp of losing eight straight when they head to Lambeau Field to take on Aaron Rodgers and the Green Bay Packers.

The Dallas Cowboys (2-7) and Carolina Panthers (3-6) seek to end a four-game skid.

Here’s our quickie NFL betting rundown for games in Week 10…

Game(s) of the Week: Buffalo at Arizona

Buffalo Bills (7-2) at Arizona Cardinals (5-3)… The Bills Mafia heads to the desert for a high-stakes showdown as one of two NFL marquee games of the week in Week 10. The Bills won three in a row since losing to the Super Bowl champs in Week 6. The Cardinals are in the top 6 in scoring (29.3 ppg) and the top 8 in scoring defense (22.5 ppg). Kyler Murray looked unstoppable in an overtime victory over the Seahawks in Week 8. However, they fell short of the mark with a three-point loss against Tua and the Dolphins last week.  The Arizona Cardinals are 1-3 against animal teams, including 0-2 against cat teams, heading into this matchup against the Buffalo Bills. LINE: Buffalo +2.5

Seattle Seahawks (6-2) at LA Rams (5-3)… Russell Wilson spearheads the highest-scoring offense in the NFL that averages 34.3 points heading into Week 10. The Rams allow only 19 points per game, or second-best in the NFL, which should make this a compelling throwdown. In terms of DVOA, the Rams D are ranked #9 overall. The Rams host the Seahawks, who come into this NFC West bout as an underdog. These two teams meet again in Week 16, which could determine the division title if the Seahawks lose this one in LA. LINE: Seattle +1.5

Bad Teams on the Road vs Good Teams

Houston Texans (2-6) at Cleveland Browns (5-3)… Houston is 1-7 ATS this season for second-worst in the NFL. The Texans and their Swiss cheese defense is the fourth-worst in the NFL allowing 30.3 points per game heading into Week 10. The Texans are the worst team in the league stopping the run by allowing 159.5 rushing yards per game. Even with Nick Chubb dinged up, the Browns boast the fifth-best rushing attack in the league averaging 150 yards per game (thanks to Kareem Hunt). LINE: Cleveland -3

Denver Broncos (3-5) at Las Vegas Raiders (5-3)… The Broncos, ranked sixth-worst in the NFL in scoring, averages 21.8 per game. The Raiders’ D is ranked #9 worst in the league allowing 28.6 points per game. With a rematch against Kansas City looming for Week 11, the Raiders could get caught with their pants down if they’re looking ahead to next week. LINE: Las Vegas -4

San Francisco 49ers (4-5) at New Orleans Saints (6-2)… Did you know that the Saints now have the top-rated defense according to DVOA? Who Dat nation destroyed the Bucs twice this season, including a 38-3 whooping last weekend. LINE: New Orleans -9.5

LA Chargers (2-6) at Miami Dolphins (5-3)… The Chargers lost six close games by a combined 24 points. They also lost three games by three or fewer points. Justin Herbert continues to improve every game. The former Oregon QB is one of the co-favorites to win rookie of the year. The Dolphins are 6-2 ATS and 2-0 ATS since Tua took over at quarterback. LINE: Miami -1.5

Losing Cat Teams

Washington (2-6) at Detroit Lions (3-5)… If it weren’t for the Giants/Eagles bum fight, this would be in contention for the ‘Poo Emoji Game of the Week’. It looks like Alex Smith will get the start because Kyle Allen suffered a brutal injury last week. LINE: Detroit -4

Jacksonville Jaguars (1-7) at Green Bay Packers (6-2)… The Packers finally have Devante Adams and Aaron Jones healthy. Green Bay’s Golden Boy, the legendary Paul Hornung, passed away this week. The Packers will be fired up to win this game for one of their all-time greatest players. Heading into Week 19, Green Bay is 6-2 ATS (tied for best in the NFL). LINE: Green Bay -13.5

Cincinnati Bengals (2-5-1) at Pittsburgh Steelers (8-0)… Big Ben is out with COVID, but Mason Rudolph will take over. Joe Burrow and the Bengals are 6-2 ATS this season, despite just two wins. We jumped on the Bengals when the line opened +10, but it’s since moved to a touchdown plus the hook. LINE: Cincy +7.5

Tampa Bay Bucs (6-3) at Carolina Panthers (3-6)… Tom Brady and the Bucs are 2-0 this season after a loss. Five out of six of Carolina’s losses were within one score, including three that were four points or less. Teddy Bridgewater and the Panthers gave Kansas City a scare last Sunday, but fell short 33-31. LINE: Tampa Bay -5.5

NFL Week 10: Poo Emoji Game of the Week

Philadelphia Eagles (3-4-1) at New York Giants (2-7)… Yikes, this stinker is definitely not Buffalo and Arizona. An NFC East matchup with the worst division in the NFL gets the nod as the crap game of the week in Week 10. The Eagles are fresh off a bye week. They’re also finally getting healthy players back in the mix, like RB Miles Sanders. LINE: Philly -3.5

Prime Time: L-Jax and D-Cook

SNF: Baltimore Ravens (6-2) at New England Patriots (3-5)… The Ravens are fresh off a bye week. The Patriots play on short rest. They were nearly embarrassed last week when they almost lost to the LOL Jets. Nick Folk drilled a game-winning field goal to save the Pats. LINE: Baltimore -7

MNF: Minnesota Vikings (3-5) at Chicago Bears (5-4)… Da Bears are a home dog on Monday Night Football? Despite missing one game, Dalvin Cook is the top rusher in the NFL heading into Week 10. Da Bears started the season 5-1 and desperate to stop their three-game skid. LINE: Chicago +2.5

Leave a Reply

Your email address will not be published. Required fields are marked *